Bay 65-1942 R form

CAS No. 758683-21-5

Bay 65-1942 R form( Bay 65-1942 | Bay 65 1942 )

Catalog No. M15884 CAS No. 758683-21-5

The R form of Bay 65-1942. which is a potent, selective, ATP-competitive inhibitor of IKKβ kinase with Ki of 2 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Bay 65-1942 R form
  • Note
    Research use only, not for human use.
  • Brief Description
    The R form of Bay 65-1942. which is a potent, selective, ATP-competitive inhibitor of IKKβ kinase with Ki of 2 nM.
  • Description
    The R form of Bay 65-1942. which is a potent, selective, ATP-competitive inhibitor of IKKβ kinase with Ki of 2 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Bay 65-1942 | Bay 65 1942
  • Pathway
    Immunology/Inflammation
  • Target
    IκB kinase (IKK)
  • Recptor
    IκB kinase (IKK)
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    758683-21-5
  • Formula Weight
    395.4516
  • Molecular Formula
    C22H25N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    C1CC(CNC1)C2=CC(=NC3=C2COC(=O)N3)C4=C(C=CC=C4OCC5CC5)O
  • Chemical Name
    2H-Pyrido[2,3-d][1,3]oxazin-2-one, 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-1,4-dihydro-5-(3R)-3-piperidinyl-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ziegelbauer K, et al. Br J Pharmacol. 2005 May;145(2):178-92.
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